BDBM50059318 CHEMBL3393356::US9156845, 78

SMILES Fc1c(cccc1-c1c[nH]c2ncnc(N3CCOCC3)c12)C#N

InChI Key InChIKey=YIDVVQGSCVWPGO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059318   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM50059318(CHEMBL3393356 | US9156845, 78)
Affinity DataIC50:  7nMpH: 7.5Assay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...More data for this Ligand-Target Pair
In DepthDetails US Patent